Research in Dr. Jayaprakash's lab focuses on understanding remote memory - the ability to remember things that happened a while ago - and its role in creative problem solving. One of the mechanisms of memory storage is thought to be the formation of new and/or differential strengthening of existing neuronal connections. Scientists have found it extremely difficult to follow these changes directly as they happen following a learning event. This is primarily because of technical limitations of not being able to follow neuronal activity in the deep brain structures. Dr. Jayaprakash's lab therefore aims to develop methods that are capable of following these changes deep inside live mice brains following behavioural training.